Wormin contains mebendazole. It is hightly effective and safe anthelmintic. It is useful in a wide range of single and mixed worm infestations. It is methyl (5- benzoylbenzimidazole -2- ylcarbamate.)
Each tablet of wormin 500 contains.
Mebendazole U.S.P 500mg
MODE OF ACTION:
Wormin exerts a local action on the worms in the gastro-intestinal tract. It inhibits the glucose uptake of worms irreversibly resulting in parasite immobilization and death, worm clearance from the gastro-intestinal tract may occur up to 3 days after treatment. Wormin also inhibits the development of ova and larval froms.
Wormin is poorly absorbed from the gastro-intestinal from of decarboxylated metabolite. This poor absorption contributes to almost compelet lack of side effects with mebendazole.
Wormin is effective agasinst large number of worms. Being broad spectrum in nature it is recommeded in single as well as mixed infestation. It is useful in the treatment of follwing worm infestation.
Ascaris lumbricoides (round worm)
Ancylostoma duodenale (old world hook worm)
Necator americanus (new world hook worm)
Enterobius vemicularis (thred worm or pin worm)
Trichuris trichiura (whip worm)
Wormin has also been found to be effective in following worm infestations.
Taenia saginata (beef tape worm)
Taenia solium (pork tape worm)
Trichinosis (hydatid cyst)
DOSAGE & ADMINISTATION:
Wormin is given orally in a single no special preparation like fasting or purging is required.
If the patient is not cured in 3 week after treatment a second course of wormin may be given. In hydatid cyst medical therapy with high dose mebendazole (40mg/kg/day) has been used successfully.
Pregnancy and hypersensitivity to mebendazole.
The drug has been extensively studied in children under one year, therfore in the treatment of children below one year the benefits should be weighed against possible hazards.
WORMIN is virtually free from side effects. Transient abdominal pain and diarrhoea have beeen reported only rarely in cases of massive infestation of worms,. As a result of poor absorption mebendazole does not cause systemic toxicity in clinical use.
TEMPERRATURE BETWEEEN 15 0C & 25OC