V.I-A.G-R.A is indicated in adult men with erectile dysfunction, which is the inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
In order for V.IA-G.R-A to be effective, sexual stimulation is required.
* Patients should not use V-I.A.G-R.A if sexual activity is inadvisable due to cardiovascular status
* Patients should seek emergency treatment if an erection lasts >4 hours. Use V.I-A.G-R-A with caution in patients predisposed to priapism
Patients should stop V.I.A-G.R-A and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). V-I.A-G.R-A should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION.
* Patients should stop V-I.A.G.R.A and seek prompt medical attention in the event of sudden decrease or loss of hearing
* Caution is advised when V.I.A.G.R.A is co-administered with alpha-blockers or anti-hypertensives. Concomitant use may lead to hypotensio
* Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures. In patients taking strong CYP inhibitors, such as ritonavir, sildenafil exposure is increased. Decrease in V.I.A.G.R.A dosage is recommended
Most common adverse reactions include headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash
For most patients, the recommended dose is 50mg taken, as needed, approximately 1 hour before sexual activity. However, V.I-A.G-R.A may be taken anywhere from 30 minutes to 4 hours before sexual activity.
The maximum recommended dosing frequency is once per day.
Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 50mg